COVID-19 Research Inventory List

Note: This inventory is a work in progress and is not a complete list; it may also include studies that have not yet been approved to start.

IDTitleLead OrganizationDescriptionBC Lead Investigator(s)Funder(s)
1CATCO: Canadian Treatments for COVID19UBCA randomized, controlled trial of lopinavir/ritonavir in hospitalized patients with confirmed COVID19.Srinivas MurthyCIHR
3SARS-CoV-2 Rapid Research: Fast track isothermal viral diagnosticsSFUThe Unrau laboratory at Simon Fraser University has engineered an isothermal RNA detection kit that reports the presence of RNA template by fluorogenic aptamer (RNA Mango) synthesis in a simple fluorogenic assay (Mango NASBA). This technology, which…Peter J Unrau, Masahiro NiikuraCIHR
4Augmented Discovery of Potential Inhibitors of SARS-CoV-2 3CL ProteaseUBCWe have recently established a powerful Deep-Learning accelerated Docking pipeline to virtually screen a commercial 1.3-billion-compound library in a matter of one week--compared to the three years with previous programs. We have applied this novel…Arterm CherkasovCIHR
5Host cellular protein substrates of SARS-CoV-2 proteasesUBCIn this study, we will identify the host proteins that are targeted by a viral protein called a protease using an unbiased proteomics approach. Identifying the protein targets of SARS/MERS-CoV proteases will reveal into the protein sequence that binds to…Eric JanCIHR
6Neutralizing human-derived single-chain antibodies against SARS-CoV-2UBCThe objectives of this application are 1) to develop antibodies that will block the entrance of the virus into the cells, and to test the efficacy of these antibodies in mice.Horacio BachCIHR
8Genomic epidemiology and evolutionary dynamics of COVID-19 and other emerging corona virusesUBCWe will study the genomic evolution of SARS-CoV-2 to investigate if particular motifs are under selection for increased virulence and immune evasion. We will compare SARS-CoV-2 with genomes of other zoonotic coronaviruses to elucidate common genomic…Jeffrey JoyCIHR
9Understanding compliance with the International Health Regulations (2005): Recommended strategiesSimon Fraser UniversityThe goal of this project is to strengthen global coordination of the COVID-19 outbreak response through a fuller understanding of crossborder measures adopted, their likely positive/negative impacts, reason(s) for adoption, and strategies to increase…Kelley LeeCIHR Operating Grant: Canadian 2019 Novel Coronavirus (COVID-19) Rapid Research Funding Opportunity.
10Wuhan Interview: Human Experiences During the COVID-19 Outbreak in WuhanUBCWe will conduct interviews with 120 adults who lived in Wuhan during the quarantine to examine how people understood, reacted to, and coped with the quarantine, and what local barriers, challenges, and needs existed in combating the outbreak. This…Yue QianCIHR: City shutdown as a response to COVID-19: understanding human experiences and mental health co
12Understanding and mitigating real-time differential gendered effects of the COVID-19 outbreakSimon Fraser UniversityThe impact of disease on individuals and communities is not homogenous, with women disproportionately infected and affected. However, public health efforts to effectively contain an outbreak, and mitigate its secondary impacts, remain hindered…Kelley Lee, Julia SmithCIHR, Canadian 2019 Novel Coronavirus (COVID-19) Rapid Response Fund
13Developing COVID-19 Risk Communication and Community Engagement Readiness Strategy Guidance for TravUniversity of the Fraser ValleyPeople who travel back to their countries of origin to visit friends and relatives (VFR) (including the children of immigrants and international students) are often at a higher risk of getting the disease and then spreading it to others. A better…Cynthia JardineCIHR
14Inoculating Against an Infodemic: Microlearning Interventions to Address CoV MisinformationRoyal Roads UniversityThe effort seeks to improve personal health and the health of populations by combating misinformation and developing online learning interventions that improve people's knowledge, skills, beliefs, and behaviours related to COVID-19. In particular,…George VeletsianosCIHR
15CoRa Study: SARS-CoV-2 Rapid Research: Fast track isothermal viral diagnostics (CoRa)Providence Health Care - St. Paul's HospitalCOVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). With no treatment or vaccine currently available, it is imperative that rapid, sensitive, and simple screening technologies be developed that can be fully…Don SinCanadian Institutes of Health Research (CIHR)
21COVID-19 Immunity Study: COVID-19 Immunological Investigation: Quality, Quantity and Kinetics of AntBC Centre for Disease ControlTo validate SARS-CoV-2 antibody assays in development and to evaluate the type, quantity, quality and kinetics of the immune response. To collect blood from confirmed COVID-19 cases to enable validation of antibody assays, guide timing of specimen…Danuta SkowronskiMSFHR
22COVID-19 SeroSurvey: CORONAVIRUS DISEASE 2019 (COVID-19): SERIAL ANONYMIZED SERO-SURVEYS TO ASSESSBC Centre for Disease Controlwe will collect a series of four snapshots consisting of 1000 anonymized residual blood serum samples (i.e. 4000 sera in total) from residents of the Lower Mainland, British Columbia attending LifeLabs for other diagnostic testing. At the individual…Danuta SkowronskiMSFHR
23Tracking the transmission of COVID-19BC Centre for Disease ControlThe time-sensitive collection of anonymized sera from residents of BC for the purposes of investigation to establish baseline susceptibility and cross-reactivity, and subsequent population level changes in sero-susceptibility/sero-prevalence to derive…Michael OtterstatterMSFHR